Antiulcer and hepatoprotective effects of Semicarpus anacardium Linn. seed extract
نویسندگان
چکیده
The antiulcer effect of Semicarpus anacardium Linn. seed extracts was investigated against aspirin plus pylorus ligation induced and ethanol induced gastric ulcers in rats. Both the models revealed ulcer healing property of the seed extracts. The present investigation also revealed the hepatoprotective activity of the seed extracts, against ethanol induced hepatotoxicity. Histopathological studies of the liver showed significant restoration of the normal histomorphological pattern of hepatocytes. The biochemical estimation of serum bilirubin, serum glutamate pyruvate transaminase (SGPT), serum glutamate oxaloacetate transaminase (SGOT) and alkaline phosphatase (ALP) showed significant reduction in the rats fed with the seed extracts. The study, thus, substantiates the potential anticulcer and hepatoprotective effects of Semicarpus anacardium seeds.
منابع مشابه
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